The toss was won by Sri Lanka, who elected to field first in this opening fixture of the Emerging Nations Trophy.
Hunter faced Sathy Sandeepani on her debut as vice-captain in Orla Prendergast's absence, while Little was dismissed by Nilakshi de Silva following her highest individual score of the match.
Laura Delaney reached 15 runs before leaving the crease in the same over that saw Little exit, and debutant Abi Harrison survived on 13 not out to keep Ireland close to a century.
Despite crossing the hundred mark, momentum shifted as Cara Murray, Jane Maguire and Kia McCartney were all removed in consecutive overs, leaving Sri Lanka in a commanding position.
Vishmi Gunaratne and Hasini Perera formed an unbeaten partnership of 53 runs each, helping the hosts reach the target in just thirteen overs.
Gunaratne scored 53 from thirty-seven balls including six boundaries, while Perera matched that tally from forty-one deliveries with eight fours and a six.
Captain Gaby Lewis was dismissed for four runs, and Lara Maritz added 13 before being caught by Kavisha Dilhari who took her wicket on debut.
Ireland will resume their group campaign against Papua New Guinea on Monday and face Scotland on Wednesday in the tournament.
Lloyd Tennant's side now look to progress to Friday's scheduled match against the United Arab Emirates at City of Derry Airport.
The Emerging Nations Trophy continues its expansion across the region with multiple nations competing for qualification spots.
This result marks a significant achievement for Sri Lanka Women as they extend their unbeaten run in international cricket.
AjmanIreland Women will review their batting collapse and fielding errors ahead of their next encounter.
The victory strengthens Sri Lanka's position as they aim to secure a spot in the final stages of the competition.
Lloyd Tennant will analyse the performance data before preparing his squad for Friday's fixture against UAE.
City of Derry Airport remains the venue for all upcoming fixtures in this regional tournament.
Sri Lanka Women have now demonstrated their ability to chase down targets efficiently in T20 format cricket.
The Emerging Nations Trophy organisers confirmed the schedule includes matches against Papua New Guinea and Scotland.
Amy Hunter's vice-captaincy role was a key factor in her performance during the opening innings.
Louise Little's 28 runs provided crucial support before the collapse in the final overs.
Kavisha Dilhari's debut included taking two wickets for Sri Lanka Women in this match.
Hasini Perera and Vishmi Gunaratne formed a dominant partnership that secured the win.
The hosts will now focus on maintaining their momentum against Papua New Guinea next week.
Sri Lanka's victory highlights the growing competitiveness of women's cricket in the region.
AjmanIreland Women's management will assess the impact of Prendergast's absence from the squad.
Nilakshi de Silva and Sathy Sandeepani were named as key performers for Sri Lanka Women after the match.
The Emerging Nations Trophy continues to attract significant interest across Northern Ireland and beyond.
Lloyd Tennant's team will use this result as motivation for their upcoming fixtures.
City of Derry Airport hosted the opening game of the tournament with full attendance.
Sri Lanka Women have now established themselves as a formidable force in international cricket.
The match concluded with Sri Lanka Women winning by ten wickets in a decisive performance.
AjmanIreland Women's campaign will continue against Papua New Guinea on Monday.
Lloyd Tennant's side faces Scotland on Wednesday before their next group game.
Sathy Sandeepani and Nilakshi de Silva were the main bowlers for Sri Lanka Women in this contest.
The Emerging Nations Trophy organisers have confirmed the full schedule for the tournament.
Amy Hunter's vice-captaincy appointment was made prior to the start of the competition.
Louise Little's 28 runs were her highest individual score in international cricket so far.
Kavisha Dilhari took two wickets including that of Lara Maritz during the innings.
Hasini Perera and Vishmi Gunaratne formed an unbeaten partnership of 53 runs each.
The hosts will now focus on maintaining their momentum against Papua New Guinea next week.
Sri Lanka's victory highlights the growing competitiveness of women's cricket in the region.
AjmanIreland Women's management will assess the impact of Prendergast's absence from the squad.
Nilakshi de Silva and Sathy Sandeepani were the main bowlers for Sri Lanka Women in this contest.
The Emerging Nations Trophy continues to attract significant interest across Northern Ireland and beyond.
Lloyd Tennant's team will use this result as motivation for their upcoming fixtures.
City of Derry Airport hosted the opening game of the tournament with full attendance.
Sri Lanka Women have now established themselves as a formidable force in international cricket.
The match concluded with Sri Lanka Women winning by ten wickets in a decisive performance.