Ireland head coach Scott Bemand has announced two alterations to his starting XV ahead of the upcoming match against South Africa in Cape Town.
The national team aims to secure a consecutive triumph over their rivals in the Springboks Test series.
Ulster prop Sophie Barrett is set to make her second appearance in a Test fixture, joining the bench contingent.
Sadhbh McGrath has been excluded from the matchday twenty-three squad and will not feature in this contest.
Dannah O'Brien retains possession of the number ten jersey following her performance last week when she contributed ten points to a forty-seven point victory at Athlone Stadium.
Niamh Gallagher is appointed as full-back, displacing Stacey Flood from that position.
Aoibheann Reilly returns to the scrum-half role after Emily Lane has been moved to the substitutes list.
The back three consists of Trailfinders' Gallagher alongside Beibhinn Parsons and Robyn O'Connor.
Anna McGann and Aoife Dalton continue their roles in midfield for the opening period.
Linda Djougang, who scored two tries in the previous encounter, lines out at lock position together with Neve Jones and Eilis Cahill.
Jane Clohessy and Dorothy Wall occupy the other lock spots while Fiona Tuite-O'Sullivan, captain Erin King and Brittany Hogan form the back row.
The bench includes Beth Buttimer, Niamh O'Dowd, Grace Moore, Jemima Adams Verling, Eve Higgins and Stacey Flood.