The emergency services responded to the incident at the Clearway Disposals recycling facility in Belfast Harbour following reports of a major blaze that erupted after midday on Wednesday.
Firefighters are currently working to contain the flames using aerial appliances, while the Queens Road remains closed at its junction with Wolff Road as the situation develops.
The site houses approximately 4,500 tonnes of metal and cars, creating a significant hazard for the ongoing fire.
Authorities have stated that a lithium battery is the most probable cause of the outbreak.
This event mirrors a similar incident that occurred in May at the same location, where the fire lasted for more than 24 hours.
The blaze has been described as ongoing by those on the scene, with no immediate indication of when it might be fully extinguished.
Clearway Disposals is the organisation operating the recycling facility where the incident took place.
Belfast Harbour continues to experience disruption due to the fire at this industrial site.